Composition:

Contains per 1 ml:

Cloprostenol (as sodium)      0.25 mg

Description:

Cloprostenol (as sodium) is a synthetic prostaglandin analogue structurally related to prostaglandin F2α (PGF2α). As a potent luteolytic agent it causes functional and morphological regression of the corpus luteum (luteolysis) .

Indications:

Horses:
– Induction of luteolysis following early foetal death and resorption
– Termination of persistent dioestrus
– Termination of pseudopregnancy
– Treatment of lactation anoestrus
– Establishing oestrous cycles in barren/maiden mares
Cattle:
– Suboestrus or non-detected oestrus
– Induction of parturition
– Termination of normal pregnancy
– Termination of abnormal pregnancy
– Hydrops of the foetal membranes
– Chronic endometritis (pyometra)
– Ovarian luteal cysts

Contraindications:

Do not administer to pregnant animals, unless the objective is to terminate pregnancy.

Do not administer intravenously. .
Do not use in mares suffering from acute or subacute gastrointestinal or respiratory disorders.

Side Effects:

Increased body temperature and salivary secretion in cattle; sweating, increased respiratory and heart rates, ataxia, watery diarrhoea and signs of mild abdominal pain in mares.
When used for induction of parturition or abortion in cattle, an increased incidence of retained foetal membranes (retention secundinarum) or metritis may be observed.

Dosage:

For intramuscular administration.
Thoroughbreds, hunters and heavy horses: single dose of 1 – 2 ml (equivalent to 250 – 500 µg cloprostenol).
Mares: single dose of 1 – 2 ml (equivalent to 250 – 500 µg cloprostenol)
Ponies & donkeys: single dose of 0.5 – 1 ml (equivalent to 125 – 250 µg cloprostenol)
Cattle: single or repeat doses of 2 ml (equivalent to 500 µg cloprostenol)
Goats: single dose of 0.4 – 0.8 ml (equivalent to 100 – 200 µg cloprostenol)

Withdrawal Times

– For meat: 1 days.
– For milk: 0 days.

Packaging:

Bottle of 10 ml.

FOR VETERINARY USE ONLY